PURPOSENearly all men with prostate cancer treated with androgen receptor (AR) signaling inhibitors (ARSIs) develop resistance via diverse mechanisms including constitutive activation of the AR pat...
PURPOSEMany patients and physicians remain concerned about the potential detrimental effects of pregnancy after breast cancer (BC) in terms of reproductive outcomes and maternal safety. This system...
ABSTRACT Background ROS1 fusions are oncogenic drivers in 1-3% of non-small cell lung cancers (NSCLCs). The activity of immune checkpoint inhibitor (ICI) monotherapy or in combination with chemotherapy (chemo-ICI) in these tumors and their immunophenotype have not been systematically described. Patients and Methods In this multi-institutional retrospective study, tumor PD-L1 expression and tumor mutational burden (TMB) were assessed in patients with ROS1-rearranged NSCLC. Time to treatment disco...
PURPOSETo analyze the prevalence of homologous recombination deficiency (HRD) in patients with pancreatic ductal adenocarcinoma (PDAC).MATERIALS AND METHODSWe conducted a systematic review and meta...
Last. Hongming Pan(ZJU: Zhejiang University)H-Index: 23
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PURPOSEDonafenib, a novel multikinase inhibitor and a deuterated sorafenib derivative, has shown efficacy in phase Ia and Ib hepatocellular carcinoma (HCC) studies. This study compared the efficacy...
PURPOSEThe majority of young adults with Hodgkin lymphoma (HL) are cured, but chemotherapy-induced infertility can have profound psychosocial consequences. Providing data on parenthood rates and us...