Association ofKlotho-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who CarryAPOE4
Abstract
Importance
Identification of genetic factors that interact with the apolipoprotein e4 (APOE4) allele to reduce risk for Alzheimer disease (AD) would accelerate the search for new AD drug targets.Klotho-VS heterozygosity (KL-VSHET+status) protects against aging-associated phenotypes and cognitive decline, but whether it protects individuals who carryAPOE4from AD remains unclear.Objectives
...Paper Details
Title
Association ofKlotho-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who CarryAPOE4
Published Date
Jul 1, 2020
Journal
Volume
77
Issue
7
Pages
849 - 849
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Notes
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