Potential applications for rhIGF-I: Bone disease and IGF I
Abstract
Growth hormone (GH) and insulin like growth factor-I (IGFI) are key bone trophic hormones, whose rising levels during puberty are critical for pubertal bone accrual. Conditions of GH deficiency and genetic resistance impact cortical and trabecular bone deleteriously with reduced estimates of bone strength. In humans, conditions of undernutrition (as in anorexia nervosa (AN), or subsequent to chronic illnesses) are associated with low IGF-I...
Paper Details
Title
Potential applications for rhIGF-I: Bone disease and IGF I
Published Date
Jun 1, 2020
Volume
52
Pages
101317 - 101317
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