Identification of Protein Expression Changes in Hepatocellular Carcinoma through iTRAQ

Hepatocellular carcinoma (HCC) is a malignant tumor associated with a poor prognosis. Serum biomarkers of HCC have the potential to improve the diagnosis, provide a means to monitor the tumors, and predict their malignancy. Proteins that are expressed differentially between HCC patients and normal controls have the potential to be biomarkers.Serum samples from 10 confirmed HCC patients and 10 controls were collected. The differentially expressed...