Regulation of Runx2 by post-translational modifications in osteoblast differentiation
Abstract
Osteogenesis is the process of new bone formation where transcription factors play an important role in controlling cell proliferation and differentiation. Runt-related transcription factor 2 (Runx2), a key transcription factor, regulates the differentiation of mesenchymal stem cells into osteoblasts, which further mature into osteocytes. Runx2 acts as a modulator such that it can either stimulate or inhibit the osteoblast differentiation. A...
Paper Details
Title
Regulation of Runx2 by post-translational modifications in osteoblast differentiation
Published Date
Mar 1, 2020
Journal
Volume
245
Pages
117389 - 117389
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