Circulating ceramide ratios and risk of vascular brain aging and dementia

Volume: 7, Issue: 2, Pages: 160 - 168
Published: Jan 16, 2020
Abstract
We determined the association between ratios of plasma ceramide species of differing fatty-acyl chain lengths and incident dementia and Alzheimer's disease (AD) dementia in a large, community-based sample.We measured plasma ceramide levels in 1892 [54% women, mean age 70.1 (SD 6.9) yr.] dementia-free Framingham Offspring Study cohort participants between 2005 and 2008. We related ratios of very long-chain (C24:0, C22:0) to long-chain (C16:0)...
Paper Details
Title
Circulating ceramide ratios and risk of vascular brain aging and dementia
Published Date
Jan 16, 2020
Volume
7
Issue
2
Pages
160 - 168
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