Emer R. McGrath
Harvard University
Framingham Heart StudyFramingham Risk ScoreInternal medicineSurgeryOdds ratioCardiologyRandomized controlled trialPhysical therapyProspective cohort studyCohort studyHazard ratioAntithromboticAtrial fibrillationDementiaMyocardial infarctionRisk factorStrokeMedicineCohortBlood pressure
47Publications
10H-index
408Citations
Publications 46
Newest
#1Emer R. McGrath (Harvard University)H-Index: 10
#2Jayandra J. Himali (BU: Boston University)H-Index: 32
Last. Sudha Seshadri (BU: Boston University)H-Index: 95
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#1Emer R. McGrath (National University of Ireland, Galway)H-Index: 10
#2Jayandra J. HimaliH-Index: 32
Last. Sudha Seshadri (University of Texas at Austin)H-Index: 95
view all 13 authors...
Background GDF15 (growth differentiation factor 15) and NT-proBNP (N-terminal pro-B-type natriuretic peptide) may offer promise as biomarkers for cognitive outcomes, including dementia. We determined the association of these biomarkers with cognitive outcomes in a community-based cohort. Methods and Results Plasma GDF15 (n=1603) and NT-proBNP levels (n=1590) (53% women; mean age, 68.7 years) were measured in dementia-free Framingham Offspring cohort participants at examination 7 (1998-2001). Par...
1 CitationsSource
#1A Baril (BU: Boston University)H-Index: 1
#2Alexa S. Beiser (BU: Boston University)H-Index: 3
Last. Jayandra J. HimaliH-Index: 32
view all 9 authors...
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#1A Baril (BU: Boston University)H-Index: 1
#2Alexa Beiser (BU: Boston University)H-Index: 94
Last. Matthew P. Pase (University of Melbourne)H-Index: 28
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#1Emer R. McGrath (Harvard University)H-Index: 10
#2Jayandra J. HimaliH-Index: 3
Last. Sudha Seshadri (University of Texas at Austin)H-Index: 95
view all 13 authors...
BACKGROUND: We determined the association between ratios of plasma ceramide species of differing fatty-acyl chain lengths and incident dementia and Alzheimer's disease (AD) dementia in a large, community-based sample. METHODS: We measured plasma ceramide levels in 1892 [54% women, mean age 70.1 (SD 6.9) yr.] dementia-free Framingham Offspring Study cohort participants between 2005 and 2008. We related ratios of very long-chain (C24:0, C22:0) to long-chain (C16:0) ceramides to subsequent risk of ...
3 CitationsSource
#1Matthew P. Pase (BU: Boston University)H-Index: 28
#2Jayandra J. HimaliH-Index: 3
Last. Joshua C. Bis (BU: Boston University)H-Index: 8
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Objective To test the hypothesis that the inflammatory marker plasma soluble CD14 (sCD14) associates with incident dementia and related endophenotypes in 2 community-based cohorts. Methods Our samples included the prospective community-based Framingham Heart Study (FHS) and Cardiovascular Health Study (CHS) cohorts. Plasma sCD14 was measured at baseline and related to the incidence of dementia, domains of cognitive function, and MRI-defined brain volumes. Follow-up for dementia occurred over a m...
4 CitationsSource
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#1Emer R. McGrath (Harvard University)H-Index: 10
#2Jayandra J. Himali (BU: Boston University)H-Index: 32
Last. Sudha Seshadri (University of Texas at Austin)H-Index: 95
view all 11 authors...
OBJECTIVE: To determine the association between plasma insulin-like growth factor binding protein 2 (IGFBP-2) and cognitive outcomes. METHODS: We measured plasma IGFBP-2 levels in 1596 (53% women, mean age 68.7 [SD 5.7] years) dementia-free Framingham Offspring cohort participants between 1998 and 2001. Multivariable Cox proportional hazards models related plasma IGFBP-2 to subsequent risk of incident dementia and Alzheimer's disease. MRI brain measures and cognitive performance were included as...
5 CitationsSource
#1Emer R. McGrath (Brigham and Women's Hospital)H-Index: 10
#2Jayandra J. Himali (BU: Boston University)H-Index: 32
Last. Sudha SeshadriH-Index: 95
view all 13 authors...
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