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Original paper

Modulation of nanoparticle uptake, intracellular distribution, and retention with docetaxel to enhance radiotherapy

Volume: 93, Issue: 1106, Pages: 20190742 - 20190742
Published: Nov 28, 2019
Abstract
One of the major issues in current radiotherapy (RT) is the normal tissue toxicity. A smart combination of agents within the tumor would allow lowering the RT dose required while minimizing the damage to healthy tissue surrounding the tumor. We chose gold nanoparticles (GNPs) and docetaxel (DTX) as our choice of two radiosensitizing agents. They have a different mechanism of action which could lead to a synergistic effect. Our first goal was to...
Paper Details
Title
Modulation of nanoparticle uptake, intracellular distribution, and retention with docetaxel to enhance radiotherapy
Published Date
Nov 28, 2019
Volume
93
Issue
1106
Pages
20190742 - 20190742
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