Neocortex–Cerebellum Circuits for Cognitive Processing

Classic studies have mainly focused on sensorimotor information transmitted through the two cerebellar input pathways, granule cells and climbing fibers. Recent investigations indicate that the cerebellum receives diverse reward expectation-related information via granule cells, and reward prediction error signals via climbing fibers. The cerebellum may in turn reciprocally influence brain-wide reward circuitry via output pathways from the...