Insight into the dimer dissociation process of the Chromobacterium violaceum (S)-selective amine transaminase
Abstract
One of the main factors hampering the implementation in industry of transaminase-based processes for the synthesis of enantiopure amines is their often low storage and operational stability. Our still limited understanding of the inactivation processes undermining the stability of wild-type transaminases represents an obstacle to improving their stability through enzyme engineering. In this paper we present a model describing the inactivation...
Paper Details
Title
Insight into the dimer dissociation process of the Chromobacterium violaceum (S)-selective amine transaminase
Published Date
Nov 18, 2019
Journal
Volume
9
Issue
1
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