Per Berglund
Royal Institute of Technology
Substrate (chemistry)Amine gas treatingEnantioselective synthesisCatalysisOrganic chemistryEnzymeChemistryBiocatalysisCombinatorial chemistryTransaminaseChromobacterium violaceumLipaseTriacylglycerol lipaseAlcoholKinetic resolutionCandida rugosaActive siteOrganic synthesisBiochemistryEnzyme catalysisStereochemistry
119Publications
29H-index
3,100Citations
Publications 115
Newest
#1Andrea Fiorati (Polytechnic University of Milan)H-Index: 9
#2Per Berglund (KTH: Royal Institute of Technology)H-Index: 29
Last. Davide Tessaro (Polytechnic University of Milan)H-Index: 17
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Abstract The challenging bioamination of hydrophobic substrates has been attained through the employment of a disperse system consisting of a combination of a low polarity solvent (e. g. isooctan ...
2 CitationsSource
#1Henrik Land (KTH: Royal Institute of Technology)H-Index: 11
#2Federica Ruggieri (KTH: Royal Institute of Technology)H-Index: 3
Last. Per Berglund (KTH: Royal Institute of Technology)H-Index: 29
view all 5 authors...
A protein engineering approach for expanding the substrate scope of the (S)-selective Chromobacterium violaceum amine transaminase is presented. Amino acid residues in the small binding pocket of t ...
6 CitationsSource
#1Lisa Marx (KTH: Royal Institute of Technology)H-Index: 3
Last. Per Berglund (KTH: Royal Institute of Technology)H-Index: 29
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A chemoenzymatic approach has been developed for the preparation of sertraline, an established anti-depressant drug. Ketoreductases (KREDs) were employed to yield a key chiral precursor. The biored ...
6 CitationsSource
#1Federica RuggieriH-Index: 3
#2Camilla GustafssonH-Index: 1
Last. Per BerglundH-Index: 29
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Crystal Structures Combined with Molecular Dynamics Reveal Altered Flow of Water in the Active Site of W60C Chromobacterium violaceum ω-Amino Transaminase
#1Federica Ruggieri (KTH: Royal Institute of Technology)H-Index: 3
#2Jonatan C. Campillo-Brocal (KTH: Royal Institute of Technology)H-Index: 7
Last. Per Berglund (KTH: Royal Institute of Technology)H-Index: 29
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One of the main factors hampering the implementation in industry of transaminase-based processes for the synthesis of enantiopure amines is their often low storage and operational stability. Our still limited understanding of the inactivation processes undermining the stability of wild-type transaminases represents an obstacle to improving their stability through enzyme engineering. In this paper we present a model describing the inactivation process of the well-characterized (S)-selective amine...
3 CitationsSource
#1Federica RuggieriH-Index: 3
Last. Per BerglundH-Index: 29
view all 6 authors...
Source
#1Henrik Land (KTH: Royal Institute of Technology)H-Index: 11
#2Jonatan C. Campillo-Brocal (KTH: Royal Institute of Technology)H-Index: 7
Last. Per Berglund (KTH: Royal Institute of Technology)H-Index: 29
view all 4 authors...
Biocatalysis is attracting interest in the chemical industry as a sustainable alternative in large-scale chemical transformations. However, low operational stability of naturally evolved enzymes is ...
9 CitationsSource
#1Lisa MarxH-Index: 3
#2Philipp SüssH-Index: 6
Last. Per BerglundH-Index: 29
view all 5 authors...
#1Federica RuggieriH-Index: 3
Last. Per BerglundH-Index: 29
view all 6 authors...
#1Lisa MarxH-Index: 3
#2Philipp SüssH-Index: 6
Last. Per BerglundH-Index: 29
view all 3 authors...