A systematic evaluation of single cell RNA-seq analysis pipelines

Volume: 10, Issue: 1
Published: Oct 11, 2019
Abstract
The recent rapid spread of single cell RNA sequencing (scRNA-seq) methods has created a large variety of experimental and computational pipelines for which best practices have not yet been established. Here, we use simulations based on five scRNA-seq library protocols in combination with nine realistic differential expression (DE) setups to systematically evaluate three mapping, four imputation, seven normalisation and four differential...
Paper Details
Title
A systematic evaluation of single cell RNA-seq analysis pipelines
Published Date
Oct 11, 2019
Volume
10
Issue
1
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.