Review paper
A systematic evaluation of single cell RNA-seq analysis pipelines
Abstract
The recent rapid spread of single cell RNA sequencing (scRNA-seq) methods has created a large variety of experimental and computational pipelines for which best practices have not yet been established. Here, we use simulations based on five scRNA-seq library protocols in combination with nine realistic differential expression (DE) setups to systematically evaluate three mapping, four imputation, seven normalisation and four differential...
Paper Details
Title
A systematic evaluation of single cell RNA-seq analysis pipelines
Published Date
Oct 11, 2019
Journal
Volume
10
Issue
1
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