Age- and sex-dependent effects of metformin on neural precursor cells and cognitive recovery in a model of neonatal stroke

Volume: 5, Issue: 9
Published: Sep 6, 2019
Abstract
Resident neural stem and progenitor cells, collectively termed neural precursor cells (NPCs), reside in a well-defined neurogenic niche in the subventricular zone (SVZ) and contribute to ongoing postnatal neurogenesis. It is well established that the NPC niche can alter the behavior of NPCs. NPC activation is a promising therapeutic strategy for brain repair. The drug metformin has been shown to activate neural stem cells, promote...
Paper Details
Title
Age- and sex-dependent effects of metformin on neural precursor cells and cognitive recovery in a model of neonatal stroke
Published Date
Sep 6, 2019
Volume
5
Issue
9
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