Automatic Post-Prostatectomy Planning: Potential for Improving Quality and Consistency in Clinical Trials

Dosimetric variation as a result of manual planning is a key uncertainty in radiotherapy. In clinical trials, larger dosimetric uncertainty decreases statistical power and can result in the required sample size being larger to answer the trial question. Autoplanning is designed to simplify and accelerate planning aiming at reducing time for optimization and, more importantly, reducing the inter-dosimetrist variation while improving plan quality....