Multifunctional nanoparticles for genetic engineering and bioimaging of natural killer (NK) cell therapeutics
Abstract
Recently, natural killer (NK)-based immunotherapy has attracted attention as a next-generation cell-based cancer treatment strategy due to its mild side effects and excellent therapeutic efficacy. Here, we describe multifunctional nanoparticles (MF-NPs) capable of genetically manipulating NK cells and tracking them in vivo through non-invasive magnetic resonance (MR) and fluorescence optical imaging. The MF-NPs were synthesized with a core-shell...
Paper Details
Title
Multifunctional nanoparticles for genetic engineering and bioimaging of natural killer (NK) cell therapeutics
Published Date
Aug 9, 2019
Journal
Volume
221
Pages
119418 - 119418
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