Esterified Derivatives of Panaxadiol and Their Inhibitory Effect on HL‐60, THP‐1, and PC‐3 Cell Lines

Panaxadiol is a dammarane‐type ginsenoside having high ginseng content. The 3‐hydroxy group of panaxadiol (PD) was modified by fatty acids and diacids. The modified panax glycol had enhanced anticancer activity. Twelve PD derivatives were evaluated and purified by chemical synthesis, column chromatography, co‐synthesis, and identification. The human leukemia cells THP‐1, HL‐60, and human prostate cancer cell lines PC‐3 were evaluated; PD...