Why are so many MLL lysine methyltransferases required for normal mammalian development?

Volume: 76, Issue: 15, Pages: 2885 - 2898
Published: May 16, 2019
Abstract
The mixed lineage leukemia (MLL) family of proteins became known initially for the leukemia link of its founding member. Over the decades, the MLL family has been recognized as an important class of histone H3 lysine 4 (H3K4) methyltransferases that control key aspects of normal cell physiology and development. Here, we provide a brief history of the discovery and study of this family of proteins. We address two main questions: why are there so...
Paper Details
Title
Why are so many MLL lysine methyltransferases required for normal mammalian development?
Published Date
May 16, 2019
Volume
76
Issue
15
Pages
2885 - 2898
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.