Radiotherapy-Related Lymphopenia Affects Overall Survival in Patients With Lung Cancer

IntroductionLymphopenia after radiotherapy has an adverse effect on the patient’s outcome. However, the relationship between radiotherapy dose delivery and lymphopenia is not fully understood. This work used image-based data mining to identify anatomical regions where the received dose is correlated with severe lymphopenia.MethodsA total of 901 patients with lung cancer were analyzed. A Cox model was used to assess prognostic factors of overall...