Original paper
BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival
Abstract
Malignant melanoma is one of the most difficult cancers to treat due to its resistance to chemotherapy. Despite recent successes with BRAF inhibitors and immune checkpoint inhibitors, many patients do not respond or become resistant to these drugs. Hence, alternative treatments are still required. Due to the importance of the BCL-2-regulated apoptosis pathway in cancer development and drug resistance, it is of interest to establish which...
Paper Details
Title
BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival
Published Date
Apr 24, 2019
Journal
Volume
10
Issue
5
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Notes
History