Natural occurring polysaccharides from Panax ginseng C. A. Meyer: A review of isolation, structures, and bioactivities

Published on Jul 15, 2019in International Journal of Biological Macromolecules5.162
· DOI :10.1016/J.IJBIOMAC.2019.03.229
Bin Zhao2
Estimated H-index: 2
(SPU: Shenyang Pharmaceutical University),
Chongning Lv9
Estimated H-index: 9
(SPU: Shenyang Pharmaceutical University),
Jincai Lu14
Estimated H-index: 14
(SPU: Shenyang Pharmaceutical University)
Sources
Abstract
Abstract Ginseng Radix et Rhizome, which originated from Panax ginseng C. A. Meyer, has been used as traditional medicine in Asian for >2000 years. It is famous for its healthcare and therapeutic effects. Phytochemistry studies revealed that the major components of P. ginseng are: ginsenosides, polysaccharides, small peptides and essential oil. Modern research has proved that polysaccharide is one of the most important active ingredients in P. ginseng, which also takes up the largest slice of the chemical components. However, the past research was heavily oriented towards the small molecular ginsenosides. Thus, the main purpose of the present review is to summarize the preparation process, structure and biological functions of P. ginseng polysaccharides for further science research and application in medicine.
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Panax ginseng C. A. Meyer (ginseng) has been widely used as a herb and functional food in the world. Polysaccharides are the main active components of ginseng. In this paper, the polysaccharides were sequentially extracted by 50 mM Na 2 CO 3 , 1 M KOH and 4 M KOH from ginseng roots treated sequentially with hot water, α-amylase and ethylenediaminetetraacetic acid extraction. Na 2 CO 3 -soluble ginseng polysaccharide (NGP) was fractionated into one neutral and three acidic fractions by anion exch...
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