Combined Biomarker Prognosis of Mild Cognitive Impairment: An 11-Year Follow-Up Study in the Alzheimer’s Disease Neuroimaging Initiative

Background:Biomarkers may soon be used to predict decline in older individuals. Extended follow-up studies are needed to determine the stability of such biomarker-based predictions. Objective:To examine the long-term performance of baseline cognitive, neuroimaging, and cerebrospinal fluid (CSF) bio marker-assisted prognoses in patients with mild cognitive impairment. Methods:Established, biomarker-defined cohorts of subjects with mild cognitive...