Tyrosine hydroxylase phosphorylation in vivo

Tyrosine hydroxylase ( TH ) is the rate‐limiting enzyme in the synthesis of the catecholamines dopamine, noradrenaline and adrenaline. One of the major mechanisms for controlling the activity of TH is protein phosphorylation. TH is phosphorylated at serine residues 8, 19, 31 and 40. There have been a number of previous reviews focused on TH phosphorylation in vitro and in situ . This review on TH phosphorylation in vivo has three main sections...