Species-specific maturation profiles of human, chimpanzee and bonobo neural cells
Abstract
Comparative analyses of neuronal phenotypes in closely related species can shed light on neuronal changes occurring during evolution. The study of post-mortem brains of nonhuman primates (NHPs) has been limited and often does not recapitulate important species-specific developmental hallmarks. We utilize induced pluripotent stem cell (iPSC) technology to investigate the development of cortical pyramidal neurons following migration and maturation...
Paper Details
Title
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells
Published Date
Feb 7, 2019
Journal
Volume
8
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