Bone Metastasis: Find Your Niche and Fit in

Volume: 5, Issue: 2, Pages: 95 - 110
Published: Feb 1, 2019
Abstract
Metastasis to bones is determined by both intrinsic traits of metastatic tumor cells and properties appertaining to the bone microenvironment. Bone marrow niches are critical for all major steps of metastasis, including the seeding of disseminated tumor cells (DTCs) to bone, the survival of DTCs and microscopic metastases under dormancy, and the eventual outgrowth of overt metastases. In this review, we discuss the role of bone marrow niches in...
Paper Details
Title
Bone Metastasis: Find Your Niche and Fit in
Published Date
Feb 1, 2019
Volume
5
Issue
2
Pages
95 - 110
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