Genetic variation in PLEKHG1 is associated with white matter hyperintensities (n = 11,226)
Abstract
Objective
To identify novel genetic associations with white matter hyperintensities (WMH).Methods
We performed a genome-wide association meta-analysis of WMH volumes in 11,226 individuals, including 8,429 population-based individuals from UK Biobank and 2,797 stroke patients. Replication of novel loci was performed in an independent dataset of 1,202 individuals. In all studies, WMH were quantified using validated automated or...Paper Details
Title
Genetic variation in PLEKHG1 is associated with white matter hyperintensities (n = 11,226)
Published Date
Feb 19, 2019
Journal
Volume
92
Issue
8
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Notes
History