Suppression of microRNA‐141 suppressed p53 to protect against neural apoptosis in epilepsy by SIRT1 expression

We investigated that microRNA (miRNA)‐141 protects against epilepsy‐induced apoptosis and its reaction mechanism. The serum expression of miRNA‐141 in epilepsy model mice and control volunteer was measured by quantitative reverse‐transcription polymerase chain reaction. We found that miRNA‐141 serum expression was upregulated in patients with epilepsy. Overexpression of miRNA‐141 induced nerve cell apoptosis, suppressed proliferation, promoted...