Statins: a viable candidate for host-directed therapy against infectious diseases
Abstract
Statins were first identified over 40 years ago as lipid-lowering drugs and have been remarkably effective in treating cardiovascular diseases. As research advanced, the protective effects of statins were additionally attributed to their anti-inflammatory, antioxidative, anti-thrombotic and immunomodulatory functions rather than lipid-lowering abilities alone. By promoting host defence mechanisms and inhibiting pathological inflammation, statins...
Paper Details
Title
Statins: a viable candidate for host-directed therapy against infectious diseases
Published Date
Nov 28, 2018
Journal
Volume
19
Issue
2
Pages
104 - 117
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Notes
History