Original paper
Active vaccination against interleukin‐5 as long‐term treatment for insect‐bite hypersensitivity in horses
Abstract
Insect-bite hypersensitivity (IBH) in horses is a chronic allergic dermatitis caused by insect bites. Horses suffer from pruritic skin lesions, caused by type-I/type-IV allergic reactions accompanied by prominent eosinophil infiltration into the skin. Interleukin-5 (IL-5) is the key cytokine for eosinophils and we have previously shown that targeting IL-5 by vaccination reduces disease symptoms in horses.Here, we analyzed the potential for...
Paper Details
Title
Active vaccination against interleukin‐5 as long‐term treatment for insect‐bite hypersensitivity in horses
Published Date
Nov 7, 2018
Journal
Volume
74
Issue
3
Pages
572 - 582