Allergy
IF
13.15
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10.9k
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#1Anil Mishra (Tulane University)H-Index: 61
#2Dewan S. A. Majid (Tulane University)H-Index: 34
Last. Sathisha Upparahalli Venkateshaiah (Tulane University)H-Index: 14
view all 5 authors...
BACKGROUND IL-5-dependent residential and IL-18-transformed pathogenic eosinophils have been reported; however, the role of IL-18-transformed CD274-expressing pathogenic eosinophils compared to IL-5-generated eosinophils in promoting airway obstruction in asthma has not yet been examined. METHODS Eosinophils are detected by tissue anti-MBP and anti-EPX immunostaining, CD274 expression by flow cytometry, and airway resistance using the Buxco FinePointe RC system. RESULTS We show that A. fumigatus...
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#1Yun Ma (SYSU: Sun Yat-sen University)H-Index: 4
#2Yi Wei (SYSU: Sun Yat-sen University)
Last. Hua Zhong (SYSU: Sun Yat-sen University)H-Index: 1
view all 7 authors...
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#1Aleena Banerji (Harvard University)H-Index: 47
#2Anna R. Wolfson (Harvard University)H-Index: 11
Last. Kimberly G. Blumenthal (Harvard University)H-Index: 31
view all 7 authors...
After initial reports of anaphylaxis to the messenger RNA (mRNA) COVID-19 vaccines, the Centers for Disease Control and Prevention (CDC) put forth guidance stating that patients with a history of anaphylaxis to vaccine components like polyethylene glycol (PEG) should not receive the mRNA COVID-19 vaccines.1 To address this clinical challenge and decrease vaccine hesitancy, we published an approach to guide COVID-19 vaccination in high-risk allergy individuals.2-4 While the etiology of anaphylaxi...
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#1Yan ZhaoH-Index: 18
Last. Luo Zhang (Peking Union Medical College)H-Index: 1
view all 12 authors...
BACKGROUND Recent studies have revealed that the nasal microbiota in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) is profoundly altered and is correlated with systemic inflammation. However, little is known regarding whether the microbiota can be utilized to predict nasal polyp recurrence. This study is aimed to determine whether altered nasal microbiota constituents could be used as biomarkers to predict CRSwNP recurrence. METHODS Nasal microbiota constituents were quantified...
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#1Marcus Maurer (Charité)H-Index: 91
#2Ana Giménez-Arnau (Autonomous University of Barcelona)H-Index: 49
Last. Thomas Severin (Novartis)H-Index: 17
view all 18 authors...
BACKGROUND Ligelizumab, a next-generation, humanized anti-immunoglobulin E (IgE) monoclonal antibody is in development as a treatment for patients with chronic spontaneous urticaria, whose symptoms are inadequately controlled with standard-of-care therapy. OBJECTIVE To evaluate the long-term safety and re-treatment efficacy of ligelizumab 240 mg in patients who completed the core study and extension study. METHODS This open-label, single-arm, long-term Phase 2b extension study was designed to as...
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#1Sandra PfeifferH-Index: 1
#2Marianne RaithH-Index: 4
Last. Ines SwobodaH-Index: 31
view all 11 authors...
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#1Gabriele Avino (UniPi: University of Pisa)
#2Carmen Riggioni (NUS: National University of Singapore)H-Index: 7
Last. Pasquale Comberiati (UniPi: University of Pisa)H-Index: 21
view all 3 authors...
The gastrointestinal tract is a complex ecosystem responsible for dietary nutrient absorption but also involved in defense against pathogens and toxins. Such functions are thought to result from the crosstalk between the intestinal epithelial barrier, the resident microbiota, and the gut-associated lymphoid tissue, that dynamically adapt to dietary changes and external threats to ensure efficient nutrient uptake and intestinal immune-barrier homeostasis1 .
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#1Montserrat Fernandez-Rivas (Hospital Clínico San Carlos)H-Index: 58
Last. Elizabeth Naomi Clare Mills (University of Manchester)H-Index: 2
view all 38 authors...
Background The heterogeneity and lack of validation of existing severity scores for food allergic reactions limit standardization of case management and research advances. We aimed to develop and validate a severity score for food allergic reactions. Methods Following a multidisciplinary experts consensus, it was decided to develop a food allergy severity score (FASS) with ordinal (oFASS) and numerical (nFASS) formats. oFASS with 3 and 5 grades were generated through expert consensus, and nFASS ...
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#1Joseph L Neely (UA: University of Arizona)
#2Annika Reimers (Mayo Clinic)
Last. Alfred D. Doyle (Mayo Clinic)H-Index: 13
view all 8 authors...
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#1Neera Singh (KIIT: KIIT University)H-Index: 3
#2Yolanda Diebold (University of Valladolid)H-Index: 25
Last. Andrea Leonardi (UNIPD: University of Padua)H-Index: 52
view all 4 authors...
The epithelial barrier is the first line of defense that forms a protective barrier against pathogens, pollutants, and allergens. Epithelial barrier dysfunction has been recently implicated in the development of allergic diseases such as asthma, atopic dermatitis, food allergy, and rhinitis. However, there is limited knowledge on epithelial barrier dysfunction in ocular allergy (OA). Since the ocular surface is directly exposed to the environment, it is important to understand the role of ocular...
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