Introducing a novel highly prognostic grading scheme based on tumor budding and cell nest size for squamous cell carcinoma of the uterine cervix

Recently, it has been shown for several squamous cell carcinoma tumor entities that a grading approach incorporating the factors budding activity and cell nest size strongly outperforms conventional grading algorithms with respect to its prognostic value. Here, we tested this novel approach in two completely independent cohorts of cervical squamous cell...