Johanna D Strehl
University of Erlangen-Nuremberg
CancerImmunoglobulin EPathologyOncologyCase-control studyAntibodyImmunologyImmunohistochemistryDysplasiaBiopsyEndometrial cancerCarcinomaEndometriosisCalretininGynecologyRisk factorBreast cancerMedicineBiologyImmune system
41Publications
13H-index
932Citations
Publications 41
Newest
#2Grit MehlhornH-Index: 12
Last. MC Koch
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#2Werner AdlerH-Index: 19
Last. MC Koch
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#1Frederik A. Stuebs (FAU: University of Erlangen-Nuremberg)H-Index: 2
#2Grit Mehlhorn (FAU: University of Erlangen-Nuremberg)H-Index: 12
Last. Martin C. Koch (FAU: University of Erlangen-Nuremberg)H-Index: 7
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#1Frederik A. Stuebs (FAU: University of Erlangen-Nuremberg)H-Index: 2
#2Grit Mehlhorn (FAU: University of Erlangen-Nuremberg)H-Index: 12
Last. Martin C. Koch (FAU: University of Erlangen-Nuremberg)H-Index: 7
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Abstract Purpose Colposcopy-guided punch biopsy is a cornerstone method for diagnosing vulvar diseases. The aim of this study was to evaluate the concordance rate of clinical findings in vulvar diseases during examinations, in comparison with colposcopy-directed punch biopsy. We also developed a new classification to simplify the categorization of vulvoscopic findings. Methods The concordance rate of the clinical findings was compared with the final histology results from punch biopsies. The dat...
1 CitationsSource
#1Frederik A. Stuebs (FAU: University of Erlangen-Nuremberg)H-Index: 2
#2Martin C. Koch (FAU: University of Erlangen-Nuremberg)H-Index: 7
Last. Simone K. Renner (FAU: University of Erlangen-Nuremberg)H-Index: 3
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Malignancies of the vagina are rare, but colposcopy-directed biopsies play a major role in detecting vaginal intraepithelial lesions. Data of accuracy in detecting neoplasia of the vagina are very rare compared to accuracy in detecting cervical neoplasia. The aim of this study was to evaluate the accuracy of colposcopy-directed biopsy in comparison with clinical findings of the examiner. The accuracy of colposcopy-directed biopsy was compared with the clinical finding in relation to the patient’...
2 CitationsSource
#1Carla E. Schulmeyer (FAU: University of Erlangen-Nuremberg)H-Index: 2
#2F Stübs (FAU: University of Erlangen-Nuremberg)
Last. Martin C. Koch (FAU: University of Erlangen-Nuremberg)H-Index: 7
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Purpose The current cervical cancer screening program in Germany recommends that the results showing suspected HPV infection should be further examined in specialized colposcopy units. This study aimed to correlate externally documented Pap smear results with in-house colposcopy-guided Pap cytology results and compare colposcopy-guided biopsy and postoperative histopathology results.
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Context.— Paget disease of the breast, in most cases, represents intraepidermal spread of ductal carcinoma in situ. Molecular subtypes of invasive carcinoma of the breast have prognostic and therapeutic significance and show characteristic distribution. Little is known about the distribution of molecular subtypes in Paget disease of the breast. Objectives.— To examine the distribution of molecular subtypes in Paget disease of the breast and to compare them to concurrent invasive carcinoma of the...
6 CitationsSource
#1Florian Schilling (FAU: University of Erlangen-Nuremberg)H-Index: 1
#2Carol E. Geppert (FAU: University of Erlangen-Nuremberg)H-Index: 1
Last. Samir Jabari (FAU: University of Erlangen-Nuremberg)H-Index: 10
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Based on a recently introduced immunohistochemical panel (Bachmann et al. 2015) for aganglionic megacolon (AM), also known as Hirschsprung disease, histopathological diagnosis, we evaluated whether the use of digital pathology and ‘machine learning’ could help to obtain a reliable diagnosis. Slides were obtained from 31 specimens of 27 patients immunohistochemically stained for MAP2, calretinin, S100β and GLUT1. Slides were digitized by whole slide scanning. We used a Definiens Developer Tissue ...
2 CitationsSource
#1Moritz Jesinghaus (LMU: Ludwig Maximilian University of Munich)H-Index: 16
#2Johanna D StrehlH-Index: 13
Last. Martin KochH-Index: 9
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#1Moritz Jesinghaus (TUM: Technische Universität München)H-Index: 16
#2Johanna D StrehlH-Index: 13
Last. Wilko Weichert (TUM: Technische Universität München)H-Index: 65
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A novel histopathological grading system based on tumour budding and cell nest size has recently been shown to outperform conventional (WHO-based) grading algorithms in several tumour entities such as lung, oral, and oesophageal squamous cell carcinoma (SCC) in terms of prognostic patient stratification. Here, we tested the prognostic value of this innovative grading approach in two completely independent cohorts of SCC of the uterine cervix. To improve morphology-based grading, we investigated ...
13 CitationsSource
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