TET2‐Mediated Spatiotemporal Changes of 5‐Hydroxymethylcytosine During Organogenesis in the Late Mouse Fetus

Volume: 302, Issue: 6, Pages: 954 - 963
Published: Nov 25, 2018
Abstract
Genomic DNA demethylation is important for mammalian embryonic development and organ function. 5-Hydroxymethylcytosine (5hmC) is considered a novel epigenetic marker. Ten-eleven translocation (TET) enzymes convert 5-methylcytosine (5mC) to 5hmC. To explore the dynamic changes of epigenetic modifications during organogenesis in the late mouse fetus, the regional distribution and histological localization of 5hmC and TET enzymes was investigated...
Paper Details
Title
TET2‐Mediated Spatiotemporal Changes of 5‐Hydroxymethylcytosine During Organogenesis in the Late Mouse Fetus
Published Date
Nov 25, 2018
Volume
302
Issue
6
Pages
954 - 963
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