TET2‐Mediated Spatiotemporal Changes of 5‐Hydroxymethylcytosine During Organogenesis in the Late Mouse Fetus

Genomic DNA demethylation is important for mammalian embryonic development and organ function. 5‐Hydroxymethylcytosine (5hmC) is considered a novel epigenetic marker. Ten‐eleven translocation (TET) enzymes convert 5‐methylcytosine (5mC) to 5hmC. To explore the dynamic changes of epigenetic modifications during organogenesis in the late mouse fetus, the regional distribution and histological localization of 5hmC and TET enzymes was investigated...