Original paper
Ketamine reduces aversion in rodent pain models by suppressing hyperactivity of the anterior cingulate cortex
Abstract
Chronic pain is known to induce an amplified aversive reaction to peripheral nociceptive inputs. This enhanced affective response constitutes a key pathologic feature of chronic pain syndromes such as fibromyalgia. However, the neural mechanisms that underlie this important aspect of pain processing remain poorly understood, hindering the development of treatments. Here, we show that a single dose of ketamine can produce a persistent reduction...
Paper Details
Title
Ketamine reduces aversion in rodent pain models by suppressing hyperactivity of the anterior cingulate cortex
Published Date
Sep 10, 2018
Journal
Volume
9
Issue
1