A retrospective analysis of the efficacy of immune checkpoint inhibitors (ICIs) to advanced non-small cell cancer (NSCLC) patients (pts) with central nerve system (CNS) metastasis.

e21042 Background: In clinical practice of advanced NSCLC pts, a control of CNS metastasis is important issue. Several clinical trials of ICIs have demonstrated the survival benefit in advanced NSCLC. However, the efficacy to pts with CNS lesion is unclear, because most trials exclude pts with active CNS metastasis. In order to clarify the efficacy of ICIs to NSCLC pts with CNS metastasis in real-world clinical practice, we planned the...