Original paper
Development of a yeast-based system to identify new hBRAFV600E functional interactors
Abstract
BRAFV600E is a mutant Ser-Thr protein kinase that plays a crucial role in many types of cancer, including melanoma. Despite several aspects of BRAFV600E biology have been already elucidated, the proteins that regulate its expression and activity remain largely unknown, hampering our capacity to control its unrestrained effects. Here, we propose yeast Saccharomyces cerevisiae as a model system that can be used to achieve a better understanding of...
Paper Details
Title
Development of a yeast-based system to identify new hBRAFV600E functional interactors
Published Date
Sep 20, 2018
Journal
Volume
38
Issue
8
Pages
1355 - 1366
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Notes
History