Review paper
Next-generation sequencing approaches for the study of genome and epigenome toxicity induced by sulfur mustard
Abstract
Sulfur mustard (SM) is an extensive nucleophilic and alkylating agent that targets different tissues. The genotoxic property of SM is the most threatening effect, because it is associated with detrimental inflammations and susceptibility to several kinds of cancer. Moreover, SM causes a wide variety of adverse effects on DNA which result in accumulation of DNA adducts, multiple mutations, aneuploidies, and epigenetic aberrations in the genome....
Paper Details
Title
Next-generation sequencing approaches for the study of genome and epigenome toxicity induced by sulfur mustard
Published Date
Aug 28, 2018
Journal
Volume
92
Issue
12
Pages
3443 - 3457
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