Yunes Panahi
Baqiyatallah University of Medical Sciences
CancerInternal medicineEndocrinologySurgeryDermatologyRandomized controlled trialChemistryImmunologyPlaceboOxidative stressInflammationLungCurcuminSulfur mustardAnesthesiaClinical trialMedicineBiologyGastroenterologyPharmacology
281Publications
39H-index
5,021Citations
Publications 286
Newest
#1Tannaz Jamialahmadi (IAU: Islamic Azad University)H-Index: 15
#2Yunes Panahi (BMSU: Baqiyatallah University of Medical Sciences)H-Index: 39
Last. Amirhossein Sahebkar (MUMS: Mashhad University of Medical Sciences)H-Index: 111
view all 5 authors...
Oxidative stress has a key role in the pathogenesis of type 2 diabetes mellitus. Alternative therapy with antioxidants has been tested as a potential approach to curb the effects of this disorder. Here, we present a protocol to set up a randomized double-blind placebo-controlled trial to assess the impact of treatment with a mixture of curcuminoids on a number of physiological and molecular biomarker measures with the main focus on determining the total antioxidant capacity.
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#1Behdad Shokrollahi Yancheshmeh (Semnan University)
#2Yunes Panahi (BMSU: Baqiyatallah University of Medical Sciences)H-Index: 39
Last. Zahra Zamani (FUM: Ferdowsi University of Mashhad)H-Index: 1
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Abstract null null The present paper aims to optimize the extraction conditions of Achillea kellalensis Boiss. & Hausskn., endemic to Iran, with assistance of sonication to exploit the potential health benefits of its extract. The Box-Behnken experimental design was employed to investigate the influence of the sonication amplitude (50–100%), extraction time (10–30 min), ethanol concentration (30–70%), and solvent-to-solid ratio (20:1-40:1) on responses of extraction yield, antioxidant activity (...
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#1Ali Ahmadi (BMSU: Baqiyatallah University of Medical Sciences)H-Index: 48
#2Yunes Panahi (BMSU: Baqiyatallah University of Medical Sciences)H-Index: 39
Last. Amirhossein Sahebkar (MUMS: Mashhad University of Medical Sciences)H-Index: 111
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Cardiovascular disease is one of the leading causes of mortality globally. Atherosclerosis is an important step towards different types of cardiovascular disease. The role of oxidized low-density lipoprotein (oxLDL) in the initiation and progression of atherosclerosis has been thoroughly investigated in recent years. Moreover, clinical trials have established that diabetic patients are at a greater risk of developing atherosclerotic plaques. Hence, we aimed to review the clinical and experimenta...
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#1Hamed Hosseini (Tehran University of Medical Sciences)H-Index: 11
#2Anahita Sadeghi (Tehran University of Medical Sciences)H-Index: 9
Last. Farhang Babamahmoodi (Mazandaran University of Medical Sciences)H-Index: 10
view all 15 authors...
Abstract null Introduction null After emerging the global pandemic of SARS-CoV2 some preliminary studies demonstrated the efficacy of antiviral treatments. But shortly thereafter, inconsistencies in the results of further clinical trials raised doubts on the efficacy of these agents. In this study, we aimed to evaluate the effect of Remdesivir on hospitalized COVID-19 patients’ outcomes. null Material and methods null This study was an open-label, single-armed, clinical trial on hospitalized pat...
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#1Soodeh Mahdian (IAU: Islamic Azad University)H-Index: 3
#2Mahboobeh Zarrabi (Alzahra University)H-Index: 5
Last. Somayyeh Dabbagh (Alzahra University)H-Index: 1
view all 4 authors...
Abstract Background Different approaches have been proved effective for combating the COVID-19 pandemic. Accordingly, in silico drug repurposing strategy, has been highly regarded as an accurate computational tool to achieve fast and reliable results. Considering SARS-CoV-2's structural proteins and their interaction the host's cell-specific receptors, this study investigated a drug repurposing strategy aiming to screen compatible inhibitors of FDA-approved drugs against viral entry receptors (A...
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Dendrimers are hyper-branched organic compounds characterized via a three-dimensional structure possessing functional groups on the surface. These terminals groups can be simply modified to enhance the functionality of dendrimers and produce biocompatible and versatile products. They are a promising agent for nanomedicine applications because of their unique properties, including nanoscale size, globular shape, and high reactivity, solubility in water, internal cavities, and comfortable synthesi...
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#1Mohammad NikzamirH-Index: 5
#2Abolfazl Akbarzadeh (Tabriz University of Medical Sciences)H-Index: 51
Last. Yunes PanahiH-Index: 39
view all 3 authors...
Abstract Nanotechnology is the development of engineered nanoparticles to use in biomedical applications. Nanoparticles have unique physicochemical properties for use in biomedicine, however, their cytotoxicity has demonstrated in some situations that have caused concern about their clinical application. Nanoparticles must be non-toxic and biocompatible in order to be successful in biomedical applications. Nanoparticles can easily enter the body due to their small size and reach very sensitive o...
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#1Mehdi Hassanpour (Tabriz University of Medical Sciences)H-Index: 11
#2Fateme Hajihassani (Tabriz University of Medical Sciences)H-Index: 1
Last. Amirhossein SahebkarH-Index: 111
view all 12 authors...
BACKGROUND Sulfur-(SM) and nitrogen (NM)-based mustards are mutagenic incapacitating compounds that are widely used in vesicating chemical warfare and cause toxicity in many organs especially skin. SM, as a potent vesicating agent, contributes to the destruction of skin in dermis and epidermis layers. The progression of lesion is dependent on the concentration of SM and duration of exposure. Body responses start with pruritus, erythema, edema and xerosis, which lead to the accumulation of immune...
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#1Yunes Panahi (BMSU: Baqiyatallah University of Medical Sciences)H-Index: 39
#2Amir Hossein Mohammadzadeh (BMSU: Baqiyatallah University of Medical Sciences)H-Index: 1
Last. Amirhossein Sahebkar (MUMS: Mashhad University of Medical Sciences)H-Index: 111
view all 6 authors...
Non-small cell lung cancer (NSCLC) is one of the most common types of lung cancer worldwide. It metastasizes rapidly and has a poor prognosis. The first-line treatment for most patients is a combination of chemotherapy and radiation. In many subjects, using targeted treatments alongside chemoradiation has shown a better outcome in terms of progression and quality of life for patients. These targeted treatments include small biological inhibiting molecules and monoclonal antibodies. In this revie...
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#1Yunes Panahi (BMSU: Baqiyatallah University of Medical Sciences)H-Index: 39
#2Mojtaba Mojtahedzadeh (Tehran University of Medical Sciences)H-Index: 21
Last. Amirhossein Sahebkar (MUMS: Mashhad University of Medical Sciences)H-Index: 111
view all 11 authors...
Anti-arrhythmic agents, like amiodarone, interfere at different stages of the ischemic stroke. However, amiodarone was accompanied with immunological pulmonary complications and adverse neurological effects. We hypothesize that magnesium sulfate in combination with amiodarone holds promise for stroke treatment. Thirty-six patients with confirmed diagnosis of ischemic stroke and atrial fibrillation who received bolus amiodarone were randomly assigned to magnesium sulfate every 24 h or similar vol...
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