Treatment of type 2 diabetes mellitus via reversing insulin resistance and regulating lipid homeostasis in�vitro and in�vivo using cajanonic acid A
Abstract
The present study investigated the effects of cajanonic acid A (CAA), extracted from the leaves of Cajanus cajan (L.) Millsp with a purity of 98.22%, on the regulatory mechanisms of glucose and lipid metabolism. HepG2 cells transfected with a protein‑tyrosine phosphatase 1B (PTP1B) overexpression plasmid were established. The cells, induced with insulin resistance by dexamethasone (Dex) treatment, together with type 2 diabetes mellitus (T2DM)...
Paper Details
Title
Treatment of type 2 diabetes mellitus via reversing insulin resistance and regulating lipid homeostasis in�vitro and in�vivo using cajanonic acid A
Published Date
Aug 23, 2018
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