Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain
Abstract
The mammalian brain is composed of diverse, specialized cell populations. To systematically ascertain and learn from these cellular specializations, we used Drop-seq to profile RNA expression in 690,000 individual cells sampled from 9 regions of the adult mouse brain. We identified 565 transcriptionally distinct groups of cells using computational approaches developed to distinguish biological from technical signals. Cross-region analysis of...
Paper Details
Title
Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain
Published Date
Aug 1, 2018
Journal
Volume
174
Issue
4
Pages
1015 - 1030.e16
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