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Original paper

Endoglin Expression on Cancer-Associated Fibroblasts Regulates Invasion and Stimulates Colorectal Cancer Metastasis

Volume: 24, Issue: 24, Pages: 6331 - 6344
Published: Jun 26, 2018
Abstract
Cancer-associated fibroblasts (CAF) are a major component of the colorectal cancer tumor microenvironment. CAFs play an important role in tumor progression and metastasis, partly through TGF-β signaling pathway. We investigated whether the TGF-β family coreceptor endoglin is involved in CAF-mediated invasion and metastasis.CAF-specific endoglin expression was studied in colorectal cancer resection specimens using IHC and related to...
Paper Details
Title
Endoglin Expression on Cancer-Associated Fibroblasts Regulates Invasion and Stimulates Colorectal Cancer Metastasis
Published Date
Jun 26, 2018
Volume
24
Issue
24
Pages
6331 - 6344
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