The Mechanisms of Bushen-Yizhi Formula as a Therapeutic Agent against Alzheimer’s Disease

Haobin Cai; Yunxia Luo; Xin Yan; Peng Ding; Yujie Huang; Shuhuan Fang; Rong Zhang; Yun-Bo Chen; Zhouke Guo; Jiansong Fang; Qi Wang; Jun Xu

doi:https://doi.org/10.1038/s41598-018-21468-w

doi.org/10.1038/s41598-018-21468-w

The Mechanisms of Bushen-Yizhi Formula as a Therapeutic Agent against Alzheimer’s Disease

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..., Jun Xu

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Scientific Reports4.60

Volume: 8, Issue: 1

Published: Feb 15, 2018

Abstract

Bushen-Yizhi prescription (BSYZ) has been an effective traditional Chinese medicine (TCM) prescription in treating Alzheimer's disease (AD) for hundreds of years. However, the underlying mechanisms have not been fully elucidated yet. In this work, a systems pharmacology approach was developed to reveal the underlying molecular mechanisms of BSYZ in treating AD. First, we obtained 329 candidate compounds of BSYZ by in silico ADME/T filter...

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Paper Details

Title

The Mechanisms of Bushen-Yizhi Formula as a Therapeutic Agent against Alzheimer’s Disease

DOI

doi.org/10.1038/s41598-018-21468-w

Published Date

Feb 15, 2018

Journal

Scientific Reports

Volume

8

Issue

1

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