Original paper
Autism-associated 16p11.2 microdeletion impairs prefrontal functional connectivity in mouse and human
Abstract
Human genetic studies are rapidly identifying variants that increase risk for neurodevelopmental disorders. However, it remains unclear how specific mutations impact brain function and contribute to neuropsychiatric risk. Chromosome 16p11.2 deletion is one of the most common copy number variations in autism and related neurodevelopmental disorders. Using resting state functional MRI data from the Simons Variation in Individuals Project (VIP)...
Paper Details
Title
Autism-associated 16p11.2 microdeletion impairs prefrontal functional connectivity in mouse and human
Published Date
Apr 7, 2018
Journal
Volume
141
Issue
7
Pages
2055 - 2065