Converting Spent Coffee Grounds into Bioactive Extracts with Potential Skin Antiaging and Lightening Effects

The aim of this study was to valorize spent coffee grounds (SCG) into bioactive extracts for improving skin health. These extracts were obtained by subcritical water extraction (SWE) at 100 bar and temperatures up to 220 °C, in a semicontinuous mode. They were analyzed for phenolic acids, carbohydrates, antioxidant activity (AA) measured by the DPPH assay, ROS-scavenging activity in keratinocyte cells, and elastase and tyrosinase inhibitory...