Immunohistochemical assessment of the diagnostic utility of PD‐L1: a preliminary analysis of anti‐PD‐L1 antibody (SP142) for lymphoproliferative diseases with tumour and non‐malignant Hodgkin–Reed‐Sternberg (HRS)‐like cells

Aims The programmed death 1 ( PD 1)/ PD 1 ligand ( PD ‐L1) axis plays an important role in tumour cells escape from immune control. PD ‐L1 immunohistochemistry is a useful predictor of immunotherapy response, but is still not used widely in the diagnostic setting. Here we describe results using PD ‐L1 immunohistochemistry during routine diagnostics in lymphoma. Methods and results Ninety‐one lymphoproliferative disease cases sharing tumour and...