Review paper
Alzheimer's Disease and Sleep–Wake Disturbances: Amyloid, Astrocytes, and Animal Models
Abstract
Sleep–wake abnormalities are common in patients with Alzheimer's disease, and can be a major reason for institutionalization. However, an emerging concept is that these sleep–wake disturbances are part of the causal pathway accelerating the neurodegenerative process. Recently, new findings have provided intriguing evidence for a positive feedback loop between sleep–wake dysfunction and β-amyloid (Aβ) aggregation. Studies in both humans and...
Paper Details
Title
Alzheimer's Disease and Sleep–Wake Disturbances: Amyloid, Astrocytes, and Animal Models
Published Date
Mar 21, 2018
Journal
Volume
38
Issue
12
Pages
2901 - 2910
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