Convergent Mechanisms Underlying Rapid Antidepressant Action
Abstract
Traditional pharmacological treatments for depression have a delayed therapeutic onset, ranging from several weeks to months, and there is a high percentage of individuals who never respond to treatment. In contrast, ketamine produces rapid-onset antidepressant, anti-suicidal, and anti-anhedonic actions following a single administration to patients with depression. Proposed mechanisms of the antidepressant action of ketamine include...
Paper Details
Title
Convergent Mechanisms Underlying Rapid Antidepressant Action
Published Date
Mar 1, 2018
Journal
Volume
32
Issue
3
Pages
197 - 227
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