CNS Drugs
Papers 2363
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#1John Lauriello (Thomas Jefferson University)H-Index: 48
#2Peter J. WeidenH-Index: 58
Last. Amy K. O’SullivanH-Index: 2
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BACKGROUND Continuous antipsychotic therapy is recommended as part of long-term maintenance treatment of schizophrenia, and gaps in antipsychotic treatment have been associated with increased risks of relapse and rehospitalization. Because the use of long-acting injectable (LAI) antipsychotics may reduce the likelihood of undetected medication gaps, initiating an LAI medication may affect resource utilization and costs. The LAI aripiprazole lauroxil (AL) was approved in the United States (US) in...
#1Sifat Sharmin (University of Melbourne)H-Index: 7
#2Mathilde Lefort (University of Rennes)H-Index: 1
Last. Francesco Patti (University of Catania)H-Index: 59
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Introduction null Natalizumab has proved to be more effective than fingolimod in reducing disease activity in relapsing-remitting multiple sclerosis (RRMS). Whether this association is universal for all patient groups remains to be determined. null Objective null The aim of this study was to compare the relative effectiveness of natalizumab and fingolimod in RRMS subgroups defined by the baseline demographic and clinical characteristics of interest. null Methods null Patients with RRMS who were ...
#10Meera Viswanathan (RTP: Research Triangle Park)H-Index: 33
Background null Borderline personality disorder (BPD) is a debilitating psychiatric disorder that affects 0.4-3.9% of the population in Western countries. Currently, no medications have been approved by regulatory agencies for the treatment of BPD. Nevertheless, up to 96% of patients with BPD receive at least one psychotropic medication. null Objectives null The objective of this systematic review was to assess the general efficacy and the comparative effectiveness of different pharmacological t...
#1Sina Nikayin (Yale University)H-Index: 5
#2Gerard Sanacora (Yale University)H-Index: 72
Nearly 5% of individuals in the USA had serious thoughts of suicide in 2019 and over 30% of individuals suffering with major depressive disorder reported suicidal ideation with 2 million of those reporting suicidal ideation with some level of intent. However, options to treat depressed individuals considered at imminent risk of suicide remain limited. Until the recent approval of esketamine in the treatment of patients with major depressive disorder with serious suicidal thoughts or actions, no ...
#1Anita ChevleH-Index: 1
Last. Nandkishor S. KabraH-Index: 12
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1 CitationsSource
#1Juan Song (Zhengzhou University)H-Index: 8
#2Yong Wang (Zhengzhou University)H-Index: 4
Last. Changlian Zhu (Zhengzhou University)H-Index: 53
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#1Simona Lattanzi (Marche Polytechnic University)H-Index: 27
#2Laura CanafogliaH-Index: 24
Last. Martina Fanella (Sapienza University of Rome)H-Index: 8
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In randomized controlled trials, add-on brivaracetam (BRV) reduced seizure frequency in patients with drug-resistant focal epilepsy. Studies performed in a naturalistic setting are a useful complement to characterize the drug profile. This multicentre study assessed the effectiveness and tolerability of adjunctive BRV in a large population of patients with focal epilepsy in the context of real-world clinical practice. The BRIVAFIRST (BRIVAracetam add-on First Italian netwoRk STudy) was a retrosp...
#1Christine M. Le (UWO: University of Western Ontario)H-Index: 9
#2Elizabeth Finger (UWO: University of Western Ontario)H-Index: 44
Despite significant progress in the understanding of the frontotemporal dementias (FTDs), there remains no disease-modifying treatment for these conditions, and limited effective symptomatic treatment. Behavioural variant frontotemporal dementia (bvFTD) is the most common FTD syndrome, and is characterized by severe impairments in behaviour, personality and cognition. Neuropsychiatric symptoms are common features of bvFTD but are present in the other FTD syndromes. Current treatment strategies t...
#1Yue Xu (Nanjing Medical University)
#2Nousayhah Amdanee (Nanjing Medical University)H-Index: 1
Last. Xiangrong Zhang (Nanjing Medical University)
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Antipsychotic-induced gastrointestinal hypomotility and, in particular, its manifestation of constipation are common adverse effects in patients with schizophrenia in clinical practice. Serious complications of antipsychotic-induced constipation include ileus, ischaemic bowel disease, colon perforation, aspiration pneumonia, and bacterial septicaemia, which can be life threatening if left untreated, especially in patients prescribed clozapine. The aim of this paper is to review the latest resear...
#1Rima Nabbout (University of Paris)H-Index: 59
#2Mathieu Kuchenbuch (University of Paris)H-Index: 2
Last. Paolo Curatolo (University of Rome Tor Vergata)H-Index: 69
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Epilepsy is one of the main symptoms affecting the lives of individuals with tuberous sclerosis complex (TSC), causing a high rate of morbidity. Individuals with TSC can present with various types of seizures, epilepsies, and epilepsy syndromes that can coexist or appear in relation to age. Focal epilepsy is the most frequent epilepsy type with two developmental and epileptic encephalopathies: infantile spasms syndrome and Lennox-Gastaut syndrome. Active screening and early management of epileps...
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