Using immunotherapy to boost the abscopal effect

Published on Feb 16, 2018in Nature Reviews Cancer53.03
· DOI :10.1038/NRC.2018.6
Wilfred Ngwa19
Estimated H-index: 19
(Brigham and Women's Hospital),
Omoruyi Credit Irabor3
Estimated H-index: 3
(Brigham and Women's Hospital)
+ 3 AuthorsSilvia C. Formenti79
Estimated H-index: 79
(Cornell University)
Sources
Abstract
The abscopal effect, which is the regression of metastatic cancer at distant sites during radiotherapy, is somewhat rare but can be promoted by immunotherapy. This Opinion article describes emerging concepts and limitations of using a combination of radiotherapy and immunotherapy to boost the abscopal effect.
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