Functional and structural mri connectivity associated to autobiographic memory in temporal lobe epilpepsy with uni and bilateral hippocampal sclerosis.

Structural damage associated with hippocampal sclerosis (HS) is the most common cause of temporal lobe epilepsy (TLE). TLE patients with persistent paroxysmal activity during seizures have structural and functional brain connectivity disturbances with abnormalities in the wider cortico-subcortical network. The majority of lesion studies report that mesial temporal lobe (MTL) is associated with impairment of autobiographic memory (AM), namely the...