Au-PLGA Hybrid Nanoparticles with Catalase-Mimicking and near-Infrared Photothermal Activities for Photoacoustic Imaging-Guided Cancer Therapy

Imaging-guided diagnosis and therapy has been highlighted in the area of nanomedicines. However, integrating multiple functions with high performance in one theranostic (“all-in-one”) still presents considerable challenges. Here, “all-in-one” nanoparticles with drug-loading capacity, catalase-mimetic activity, photoacoustic (PA) imaging ability and photothermal properties were prepared by decorating Au nanoparticles on doxorubicin (DOX)...